Evening Primrose Seed Oil:
- Contains Gamma lipoic acid (GLA) -essential fatty acids that help balance hormones and fight inflammation and Linolenic acid - contains fatty acids, supports Heart health, improves insulin sensitivity and Blood pressure 
- Hypertension, anxiety, and fatigue 
- Women: PMS, dysmenorrhea, endometriosis, sore breasts, fibrocystic breasts 
- Skin: Burns, atopic dermatitis (especially itching), psoriasis, eczema, and acne 
- Anti-cancer therapy - In studies, the oil has shown antiproliferative effects against breast, hepatic, prostate, and leukemia cancer cell lines 
- Benefits seen through clinical trials include diabetic neuropathy, hypertension, mastalgia, PMS, osteoporosis, and dementia.  Mixed results in trials for atopic eczema and dermatitis, rheumatoid arthritis, ulcerative colitis, diabetic lipid metabolism, and alcoholism.  
- Osteoporosis: Combined with fish oil a trial confirmed osteocalcin levels rose (a bone formation marker) and alkaline phosphatase levels dropped (indicates an increase in bone mineral density) 
     ncbi.nlm.nih.gov/pmc/articles/PMC6003444;ncbi.nlm.nih.gov/pmc/articles/PMC6116039;pubmed.ncbi.nlm.nih.gov/22414479;pubmed.ncbi.nlm.nih.gov/28555835;pubmed.ncbi.nlm.nih.gov/1185351; nccih.nih.gov/health/evening-primrose-oil; ncbi.nlm.nih.gov/pmc/articles/PMC6116039/#:~:text=Evening%20primrose
- Granica, S.;  ´nska, M.E.; Piwowarski, J.P.; Ziaja, M.; Kiss, A.K. Chemical composition, antioxidative and anti-inflammatory activity of extracts prepared from aerial parts of Oenothera biennis L. and Oenothera paradoxa Hudziok obtained after seeds cultivation. J. Agric. Food Chem. 2013, 61, 801–810
 
- The Worst Weeds Are Your Best Medicine– The Common and Weedy Plant Materia Medica ©2005 Revised 2018 David Winston, RH (AHG) 
 
- Christopher Hobbs - Herbal prescriber database
 
- Principles and Practice of Phytotherapy - Modern Herbal Medicine Simon Mills, Kerry Bone
 
- Medical Herbalism - The Science and Practice of Herbal Medicine David Hoffman